The São Paulo State Health Department confirmed a new human case of yellow fever this week, marking the 10th case in the state so far in 2026 [1].

The rise in cases signals a persistent circulation of the virus within the region. Health officials said the public should prioritize vaccination to prevent further transmission and fatalities.

According to the Secretaria de Estado da Saúde de São Paulo (SES-SP), the total death toll from the disease has reached six [2]. These fatalities occurred as the virus spread across different regions of the state. In Lençóis Paulista, located in the Bauru region, officials said a 54-year-old man died [3].

Other cases have been identified in Santo André, situated in the Grande ABC area [4]. The health department said it is reinforcing vaccination efforts in these affected zones to create a stronger immunity barrier among the local population [4].

Yellow fever is an acute viral hemorrhagic disease transmitted to humans by infected mosquitoes. While the state continues to monitor the situation, the SES-SP said vaccination remains the most effective tool for individual and collective protection [5].

Authorities are monitoring the geographical spread of the virus to determine if the outbreak is expanding into new territories. The current focus remains on increasing vaccine coverage in high-risk areas to curb the death toll [5].

The total death toll from the disease has reached six.

The confirmation of a 10th case and six deaths indicates that yellow fever remains an active public health threat in São Paulo. The distribution of cases across different regions, from the Grande ABC to Bauru, suggests the virus is not confined to a single isolated pocket, necessitating a broad, state-wide vaccination push to prevent a larger epidemic.