A major epidemiological review found that consuming too much protein may be linked to a shorter lifespan [1].
The findings challenge prevailing dietary trends that emphasize high protein intake for health and fitness. As the global protein-supplement industry has reached a value of $78 billion [4], this research suggests that exceeding certain nutritional thresholds could be counterproductive to long-term longevity.
Published in July 2024, the review analyzed data from cohorts across North America, Europe, and Asia [1]. The study included more than 1 million participants across five cohort studies [3]. Researchers said that excess protein may increase the risk of cardiovascular disease and kidney strain, both of which are associated with higher mortality [1].
"Consuming excessive protein may increase the risk of early mortality, according to a comprehensive review of epidemiological studies," the lead author of the review said [2].
While the review highlights risks of overconsumption, other health experts emphasize the importance of balance. A recommended protein intake range is generally cited as 1.2–1.6 grams per kilogram of body weight per day [5].
Registered dietitian Jane Doe said signs of getting too much protein include fatigue, digestive issues, and reduced appetite [6]. Other health reports suggest that meeting protein goals can provide benefits, such as supporting muscle health, and aiding blood-sugar control [7].
A science reporter said that the study suggests a lower-protein diet could be linked to a longer lifespan [8]. The research underscores a tension between short-term athletic or metabolic goals and long-term systemic health.
“Consuming excessive protein may increase the risk of early mortality”
This research suggests a potential 'U-shaped' relationship between protein intake and mortality, where both deficiency and excess pose health risks. By linking high protein levels to kidney strain and cardiovascular issues, the study provides a scientific caution against the unrestricted use of supplements and high-protein diets, shifting the conversation from 'more is better' to an emphasis on precise, individualized nutritional thresholds.
